Rhınocerebral Mucormycosıs

Saleem A., Moho A., Muneer M.

ABSTRACT Objective: To evaluate the effectiveness of oral systemic antifungal (fluconazol) with nasal antifungal wash and aggressive surgical debridement in treatment of rhinocerebral mucormycosis. Patients and Methods: In a prospective hospital based study, we reviewed the management of 32 patients with rhinocerebral mucormycosis in Mosul general hospital and Al-Rahma Hjospital(Mosul_Iraq), over a period of 7 years (Jan 1995 - Dec 2001). Results: 32 patients with rhinocerebral mucormycosis were adults mean age was 49 years;age range (34-64years). 18 were male and 14 were female. Diabetes mellitus was the main underlying diagnosis in our patients. The main causative agent was mucor sp..The mortality rate was 56.2%. Conclusion: Management of patients with rhinocerebral mucormycosis by oral antifungal ( fluconazol ) with nasal antifungal wash by mixture of clotrimazol and 20% sodium bicarbonate solution and aggressive surgical debridement after the control of the underlying disease, seems to be effective.

Türk Otorinolarengoloji XXVIII.Ulusal Kongresi Özetleri P4

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